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Welcome to the Southeastern Fertility Center's Home Page

The Southeastern Center for Fertility and Reproductive Surgery offers this site as an information resource for couples coping with the difficulties of infertility. Just as our center provides the most advanced treatment for our patients, this site provides the most recent and accurate medical information concerning infertility and reproductive surgery.

Located in Knoxville, Tennessee, the center specializes in the diagnosis and treatment of male and female infertility problems. Under the direction of Jeffrey A. Keenan MD, HCLD, our patients receive the highest quality medical care available in the region. Dr. Keenan is one of the most experienced and respected specialists in infertility and reproductive medicine and surgery.

We provide updates on this site to ensure you are receiving the latest information. If you wish to schedule an appointment with us or have questions, please call us at (865) 777-0088 or click here to use our appointment request form.

Dr. Jeffrey A. Keenan


Frozen More Than 24 Years, Born Perfectly Healthy!

What once sounded like science fiction became reality when a 26-year-old gave birth to an embryo frozen for more than 24 years, and it happened right here in East Tennessee! In fact, she was our patient! In late 2017, Tina Gibson gave birth to baby Emma Wren, delivering the world's longest-frozen embryo to successfully come to birth. Tina and her husband Benjamin were embryo-receiving parents through the National Embryo Donation Center and had their frozen embryo transfer (FET) performed through us. This story made global headlines! Click here to view the coverage on Good Morning America. We're so happy for the entire Gibson family!


Winter Update 2018

The staff at the Southeastern Center for Fertility and Reproductive Surgery hopes that each and every one of you have a very Merry Christmas and wishes you a prosperous and blessed New Year! We hope to see you in the New Year to assist you on your journey to start a new family or expand your current family. Call today to schedule an appointment! (865) 777-0088

Growing Southeastern Fertility Family

Our Southeastern Center for Fertility and Reproductive Surgery family is growing. Both our receptionist, Taylor and our nurse practitioner, Autumn are expecting! Taylor will be welcoming another baby girl in June, and Autumn will we welcoming another baby boy in July. Please join us in congratulating them the next time you're in the office!

Autumn is Leaving

It is with great sadness that we announce the departure of our nurse practitioner, Autumn Galbraith, WHNP-BC. Autumn has been with us 8 years but has been presented another opportunity which will allow her more time with her growing family. She will continue to work with us until we find an excellent replacement, hopefully by the first of March. Autumn's Last day will be Thursday, February 28th. Please join us in wishing her luck with her future endeavors.

Winter Observances

  • January is Birth Defects Prevention Month
  • January is Cervical Health Awareness Month
  • January is Thyroid Awareness Month
  • February is American Heart Month
  • March is National Endometriosis Awareness Month

Literature Review

Medications and Male Infertility

Have you and your partner been attempting pregnancy without success? Perhaps, you need to check the medicine cabinet. Certain medications and substances can alter male fertility through several avenues. Some recreational and illicit drugs such as alcohol, cigarettes, marijuana, opioids, and cocaine can adversely affect male fertility by killing or altering the function of sperm, altering a man's hormones, decreasing libido, and causing erectile dysfunction.

Blood pressure medications such as thiazide diuretics, spironolactone, beta-blockers, calcium channel blockers, and alpha-adrenergic blockers may also adversely affect male fertility. Speak to your primary care provider (PCP) if you are on one of the above medications to see if it may be possible to switch to another anti-hypertensive. Mental health medications such as antipsychotics, tricyclic antidepressants, MAOIs, phenothiazines, and lithium should also be used with caution if you are trying to conceive.

Cancer drugs such as alkylating agents, antimetabolites, and vinca alkaloids may make a man sterile. Freezing sperm prior to cancer treatments should be considered. Hormones such as anabolic steroids, antiandrogens, progesterone derivatives, and estrogens should be avoided when trying to conceive. If testosterone supplementation is being used or considered for low testosterone, and alternative should be chosen as testosterone supplementation can wipeout a man's sperm supply, which in many cases is reversible.

Lastly, antibiotics such as nitrofurantoin, erythromycin, tertracyclines, and gentamycin and miscellaneous medications such as cimetidine, cyclosporine, colchicine, allopurinol, and sufasalazine should also be avoided, or an alternative should be considered. Talk to your doctor about what other options you may have to avoid medication-induced infertility.

Best Practices for PCOS

There has been much research done in the area of PCOS and it's related disorders, as well as treatment for these things. Conflicting results have caused many to be confused about just what is the optimal treatment regimen for PCOS patients desiring pregnancy. In short, here are our recommendations at the SCFRS:

Letrozole is the first line drug for ovulation induction.

Metformin should be given for most patients, depending on their response and tolerance, and even normal weight women may benefit in terms of improved pregnancy rates.

There is adequate evidence at this time that CoQ-10 is beneficial for women suffering from PCOS. We also often recommend Melatonin.

Information on a "PCOS diet" is listed on this website.

BOTH aerobic and anaerobic activity (e.g. running or biking, and weightlifting) are helpful and benefit different aspects of the metabolism in this group of women.

Weight loss is helpful for women with a BMI of more than 30.

There are many exceptions to these recommendations, but they are a good starting point for women who are beginning this journey. Let us know how else we may be of assistance!